A study on clinical profile of peripheral arterial disease among people attending surgical OPD at tertiary care centre in South Kerala

Anish Immanuel P; Raveendran K; Abishek R; Basanth

A study on clinical profile of peripheral arterial disease among people attending surgical OPD at tertiary care centre in South Kerala

Authors
Anish Immanuel P, Raveendran K, Abishek R, Basanth

Abstract
Background: Peripheral Arterial Disease (PAD) is one of the common health problems in India and also globally. PAD is also associated with other Coronary Artery Disease, Cerebro Vacular Accident and erectile dysfunction. Approximately 50% of the patient having peripheral artery disease is asymptomatic; this makes it difficult to know the true prevalence of the disease in the population ^[1]. The optimal management of patients with PAD requires a comprehensive treatment strategy incorporating both lifestyle changes, including smoking cessation and exercise ^[3].

Objectives: To find out the correlation between cholesterol and PAD. To find out the correlation between PAD and selected socio-demographic variables.

Materials and Methods: A hospital-based observational study involving 55 patients was conducted in the Department of General surgery, Dr. S.M.C.S.I Medical College Karakonam, Trivandrum a tertiary care centre in south Kerala during a period of 2 years. Patient details like age, sex, clinical symptoms, Co morbidities, addictions are collected using pre-tested Questionnaire. Patients are started on Statins, Cholesterol level in the initial and after 6 months are compared.

Data Analysis: Data will be analyzed using SPSS software version 18.0V. The significant differences were tested using paired "t" test for various assessment schedule on cholesterol levels.

Results: A total of 55 adult male and female participants ≥31 years of age (mean age: 62.76 ± 10.79) years; 67.3% male and 32.7% female) were evaluated. Among the study subjects 78.2% and 74.5% were diabetic and hypertensive respectively. 41.8% and 25.5% were found to be smokers and alcoholics. 38.2% of the participants were having coronary artery disease. Mean difference between Cholesterol of first and sixth month is 78 with SD =48 (P value <0.001).

Conclusion: Peripheral vascular disease is associated with hyperlipidemia and cardiac diseases. So the effect of therapy with Atorvastatin has a major role in treating PAD patients. It also reduces the incidence of cardiac problems like angina, myocardial infarction.

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