Information and Communication Technology (ICT) is a diverse set of technological tools and resources used to communicate and to create, disseminate, store and manage information. ICT has become an essential part of all sectors and even everyday life. The National Curriculum Framework 2005 (NCF 2005) has highlighted the importance of ICT in school education. The present generation is a multimedia generation. It is known to all how computer and internet have brought revolutionary development in the world of communication. With the use of it one can move across the world not literally but virtually by being in front of the computer table. The use of ICT can boost up the teaching learning process. On the other hand, lack of proper knowledge about HIV/AIDS, its mode of transmission and ways to avoid infection, are major challenges in India. National Council of Education Research & Training (NCERT) involved in development of school curriculum package for integration of HIV/AIDS into school education (extra-curricular activities). Information and Communication Technology can offer key opportunities in building up HIV/AIDS awareness among school students, especially the adolescent students. Adolescence is shrouded in myths and misconceptions about sexual health and sexuality. During the last decade, there has been an increasing realization of the importance of adolescent behaviour.The present paper aims to discuss the use of ICT in spreading awareness of HIV/AIDS among adolescent students in India. Data were taken from some probe reports and some Government agencies and NGOs. All the data were collected by survey and information was used as secondary data.